Tuesday, July 29, 2008

The History of ProFibe

In 1973, Dr. James Cerda (gastroenterologist) and Mr. Charles Burgin (chemist) began to research the benefits of Pectin. These two have visionary minds, a fascination with medicine and organic chemistry, and an unwavering determination to find the answers to their questions. They thought of ideas and developed several theories.

With a fully equipped laboratory and a $300,000 sponsorship from Florida Department of Citrus, they studied a group of pigs and found out that grapefruit pectin prevented the narrowing of arteries and inhibited cholesterol levels even with a high fat diet.

In focusing on grapefruit pectin, they discovered a certain type of water-soluble fiber found in the rinds and membranes of the grapefruit. Consulting with previous researchers that have already recognized a connection that existed between soluble fibers and cholesterol levels, they further looked into pectin-lipoprotein interactions.

By 1988, their group had learned enough to conclude that soluble fibers have a very important role in slowing down the progression of human atherosclerosis. In fact, they only aimed at lowering cholesterol but were surprised when they found out that the formula also has regression effects.

They found this in a succeeding study which was titled “Inhibition of Atherosclerosis by Dietary Pectin in Micro Swine with sustained Hypercholesterolemia” (Circulation 1994:89:1247-53), they established that grapefruit pectin also has an effect on the pigs that already have high cholesterol.

The experiment involved feeding 15 Yucatan micro swines (which are about five-month old) with a high fat diet for 390 days. After this time, one pig was slaughtered to check for the status of the development of atherosclerosis. Then the 14 pigs that remained were divided into two groups. One group received 3% cellulose fiber while the other group took 3% grapefruit pectin (which is also fibrous). After nine months, autopsies of the animals revealed that the narrowing of the mean coronary artery was 45% in the group taking cellulose but only 24% for the group receiving the grapefruit pectin.

In one particular human study, 27 people were fed with pectin derived from grapefruit pulp and peel. One half of the group was given three tablespoons of pectin per day while the next half was given placebo. The result was a reduction of 9% in blood cholesterol level on the average, with a maximum reduction of 19%. The regimen was also linked to reduction in low-density lipoproteins blood level, which is another substance linked to heart disease.

Because of these outstanding results, ProFibe, was conceived and released commercially. Today, after several human studies and positive testimonies, ProFibe helps thousands of people in caring for their heart and overall health.


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